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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Steve Carlton | 297.0 | 1976 | |
| 2 | Bert Blyleven | 292.0 | 1978 | |
| 3 | Mike Mussina# | 290.0 | 1991 | |
| 4 | Jon Matlack* | 288.0 | 1983 | |
| 5 | John Montefusco* | 282.0 | 1980 | |
| 6 | Catfish Hunter | 281.0 | 1977 | |
| 6 | John Montefusco* | 281.0 | 1982 | |
| 8 | Mark Fidrych | 280.0 | 1977 | |
| 8 | Mike Mussina# | 280.0 | 1993 | |
| 8 | Kevin Brown# | 280.0 | 1988 | |
| 11 | Catfish Hunter | 279.0 | 1976 | |
| 12 | Bruce Ruffin# | 278.0 | 1990 | |
| 13 | Mike Harkey# | 277.0 | 1992 | |
| 13 | Jim Slaton | 277.0 | 1976 | |
| 13 | Dwight Gooden# | 277.0 | 1993 | |
| 13 | Doc Medich | 277.0 | 1976 | |
| 13 | Jon Matlack* | 277.0 | 1984 | |
| 18 | Jerry Reuss | 276.0 | 1976 | |
| 18 | Mark Fidrych | 276.0 | 1976 | |
| 20 | John Montefusco* | 275.0 | 1981 | |
| 21 | Kevin Brown# | 274.0 | 1993 | |
| 21 | Kevin Brown# | 274.0 | 1989 | |
| 23 | Vida Blue* | 273.0 | 1976 | |
| 24 | Jerry Reuss | 272.0 | 1979 | |
| 24 | John Montefusco* | 272.0 | 1979 | |
| 24 | Tom Seaver | 272.0 | 1976 | |
| 24 | Wayne Garland | 272.0 | 1976 | |
| 24 | John Montefusco* | 272.0 | 1984 | |
| 24 | Mike Mussina# | 272.0 | 1992 | |
| 30 | Mark Fidrych | 271.0 | 1978 | |
| 30 | Fergie Jenkins | 271.0 | 1976 | |
| 30 | John Montefusco* | 271.0 | 1978 | |
| 33 | Dwight Gooden# | 270.0 | 1989 | |
| 33 | Dennis Eckersley | 270.0 | 1982 | |
| 33 | Steve Rogers | 270.0 | 1976 | |
| 36 | Jim Palmer | 269.0 | 1976 | |
| 36 | Floyd Youmans# | 269.0 | 1987 | |
| 36 | John Montefusco* | 269.0 | 1976 | |
| 36 | Steve Carlton | 269.0 | 1977 | |
| 36 | Dwight Gooden# | 269.0 | 1984 | |
| 41 | Catfish Hunter | 268.0 | 1978 | |
| 41 | Ken Brett | 268.0 | 1976 | |
| 41 | Gaylord Perry | 268.0 | 1977 | |
| 41 | Bruce Ruffin# | 268.0 | 1989 | |
| 41 | Randy Johnson# | 268.0 | 1991 | |
| 41 | Rick Rhoden | 268.0 | 1982 | |
| 41 | Ed Halicki | 268.0 | 1979 | |
| 41 | Dennis Leonard | 268.0 | 1976 | |
| 41 | Dwight Gooden# | 268.0 | 1991 | |
| 50 | Erik Hanson# | 267.0 | 1992 | |
| 50 | Kevin Brown# | 267.0 | 1990 | |
| 50 | Gary Nolan | 267.0 | 1976 | |
| 50 | Greg Maddux# | 267.0 | 1990 | |
| 50 | Mike Harkey# | 267.0 | 1989 | |
| 50 | Joe Hesketh# | 267.0 | 1987 | |
| 50 | Dwight Gooden# | 267.0 | 1990 | |
| 57 | Steve Carlton | 266.0 | 1978 | |
| 57 | Randy Johnson# | 266.0 | 1993 | |
| 57 | Dave Goltz | 266.0 | 1976 | |
| 57 | Dwight Gooden# | 266.0 | 1987 | |
| 57 | Greg Maddux# | 266.0 | 1988 | |
| 57 | Kevin Appier# | 266.0 | 1993 | |
| 57 | Luis Tiant | 266.0 | 1976 | |
| 64 | Jon Matlack* | 265.0 | 1981 | |
| 64 | Dwight Gooden# | 265.0 | 1986 | |
| 64 | Ed Halicki | 265.0 | 1976 | |
| 64 | Roger Clemens# | 265.0 | 1987 | |
| 68 | Frank Pastore | 264.0 | 1984 | |
| 68 | Marty Pattin | 264.0 | 1979 | |
| 68 | Greg Maddux# | 264.0 | 1989 | |
| 71 | Jim Colborn | 263.0 | 1976 | |
| 71 | Larry Christenson | 263.0 | 1976 | |
| 71 | Roger Erickson | 263.0 | 1987 | |
| 71 | Bruce Ruffin# | 263.0 | 1993 | |
| 71 | Andy Rincon# | 263.0 | 1982 | |
| 76 | Dennis Eckersley | 262.0 | 1977 | |
| 76 | LaMarr Hoyt# | 262.0 | 1982 | |
| 76 | Burt Hooton | 262.0 | 1976 | |
| 76 | John Fulgham# | 262.0 | 1983 | |
| 76 | Dennis Eckersley | 262.0 | 1983 | |
| 76 | Bruce Kison | 262.0 | 1976 | |
| 82 | Burt Hooton | 261.0 | 1977 | |
| 82 | Rudy May | 261.0 | 1976 | |
| 82 | Jim Palmer | 261.0 | 1977 | |
| 82 | Jerry Reuss | 261.0 | 1982 | |
| 82 | Wayne Garland | 261.0 | 1978 | |
| 82 | Scott Sanderson | 261.0 | 1989 | |
| 82 | Dennis Leonard | 261.0 | 1977 | |
| 82 | Bruce Kison | 261.0 | 1977 | |
| 82 | Tommy John | 261.0 | 1976 | |
| 91 | Kevin Brown# | 260.0 | 1991 | |
| 91 | Jon Matlack* | 260.0 | 1976 | |
| 91 | Vida Blue* | 260.0 | 1980 | |
| 91 | Eric Rasmussen | 260.0 | 1976 | |
| 91 | Teddy Higuera# | 260.0 | 1990 | |
| 91 | Ken Brett | 260.0 | 1978 | |
| 91 | Mike Harkey# | 260.0 | 1993 | |
| 91 | Dennis Leonard | 260.0 | 1979 | |
| 91 | Jack Morris | 260.0 | 1979 | |
| 100 | Tom Seaver | 259.0 | 1979 |
