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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Dwight Gooden# | 3192 | 1984-1995 | |
| 2 | Dennis Eckersley | 2671 | 1976-1993 | |
| 3 | Bruce Hurst | 2656 | 1982-1994 | |
| 4 | Ed Correa# | 2515 | 1985-1995 | |
| 5 | Floyd Youmans# | 2514 | 1985-1995 | |
| 6 | Jose DeLeon# | 2461 | 1983-1995 | |
| 7 | Bill Gullickson# | 2378 | 1979-1995 | |
| 8 | Jose Rijo# | 2371 | 1984-1995 | |
| 9 | Roger Clemens# | 2344 | 1984-1995 | |
| 10 | Jon Matlack* | 2330 | 1976-1990 | |
| 11 | Scott Sanderson | 2319 | 1978-1992 | |
| 12 | Mike Scott | 2253 | 1979-1992 | |
| 13 | Kevin Brown# | 2214 | 1986-1995 | |
| 14 | Randy Johnson# | 2145 | 1989-1995 | |
| 15 | Greg Maddux# | 2098 | 1986-1995 | |
| 16 | Teddy Higuera# | 2078 | 1985-1995 | |
| 17 | Scott Garrelts# | 2059 | 1982-1995 | |
| 18 | Frank Viola# | 2034 | 1982-1994 | |
| 19 | Marty Bystrom# | 2019 | 1980-1995 | |
| 20 | Matt Young# | 1997 | 1983-1995 | |
| 21 | Bret Saberhagen# | 1984 | 1984-1995 | |
| 22 | Fernando Valenzuela | 1960 | 1980-1993 | |
| 23 | Bob Sebra# | 1959 | 1985-1995 | |
| 24 | Jack Morris | 1951 | 1977-1990 | |
| 25 | Dan Warthen | 1931 | 1976-1992 | |
| 26 | Orel Hershiser# | 1916 | 1983-1995 | |
| 27 | John Fulgham | 1875 | 1979-1994 | |
| 28 | John Candelaria | 1872 | 1976-1990 | |
| 29 | Ron Robinson# | 1857 | 1984-1995 | |
| 30 | John Montefusco* | 1837 | 1976-1985 | |
| 31 | Silvio Martinez | 1816 | 1977-1993 | |
| 32 | Pascual Perez | 1801 | 1980-1993 | |
| 33 | Vida Blue* | 1795 | 1976-1990 | |
| 34 | Bob Ojeda# | 1778 | 1982-1995 | |
| 35 | Jimmy Key# | 1766 | 1984-1995 | |
| 36 | Frank Tanana | 1760 | 1976-1988 | |
| 37 | Bruce Ruffin# | 1690 | 1986-1995 | |
| 38 | Danny Jackson# | 1669 | 1983-1995 | |
| 39 | J.R. Richard | 1648 | 1976-1988 | |
| 40 | John Tudor | 1617 | 1979-1992 | |
| 41 | Roger Erickson | 1605 | 1978-1992 | |
| 42 | Charlie Leibrandt | 1597 | 1979-1990 | |
| 43 | Erik Hanson# | 1595 | 1988-1995 | |
| 44 | Dennis Martinez | 1542 | 1976-1991 | |
| 45 | Atlee Hammaker | 1532 | 1981-1991 | |
| 46 | Kevin Gross# | 1525 | 1983-1994 | |
| 46 | Mike Morgan# | 1525 | 1979-1995 | |
| 48 | Bill C. Swift# | 1485 | 1985-1995 | |
| 49 | Al Leiter# | 1470 | 1988-1995 | |
| 50 | Joe Hesketh | 1447 | 1984-1993 | |
| 50 | Nolan Ryan | 1447 | 1976-1987 | |
| 52 | Rick Rhoden | 1446 | 1976-1992 | |
| 53 | John Smiley# | 1445 | 1986-1995 | |
| 54 | Mark Langston# | 1433 | 1984-1995 | |
| 55 | Larry McWilliams | 1430 | 1978-1989 | |
| 56 | John Smoltz# | 1417 | 1988-1995 | |
| 57 | Bruce Berenyi | 1412 | 1980-1993 | |
| 58 | Steve Carlton | 1410 | 1976-1985 | |
| 59 | Pete Falcone | 1388 | 1976-1986 | |
| 59 | Steve Rogers | 1388 | 1976-1988 | |
| 61 | Mike LaCoss | 1383 | 1978-1991 | |
| 62 | Rick Aguilera# | 1368 | 1985-1994 | |
| 63 | Kelly Downs# | 1367 | 1986-1995 | |
| 64 | Melido Perez# | 1356 | 1987-1994 | |
| 65 | Tony Brizzolara | 1347 | 1980-1991 | |
| 66 | John Butcher | 1346 | 1980-1994 | |
| 67 | Zane Smith# | 1344 | 1984-1995 | |
| 68 | Jeff D. Robinson# | 1330 | 1984-1995 | |
| 69 | Mike Parrott | 1326 | 1977-1993 | |
| 70 | David Clyde | 1323 | 1976-1990 | |
| 71 | Andy Rincon | 1320 | 1980-1994 | |
| 72 | Jamie Moyer# | 1305 | 1987-1995 | |
| 73 | Frank Pastore | 1287 | 1979-1993 | |
| 74 | Kirk McCaskill# | 1284 | 1985-1994 | |
| 75 | Juan Nieves# | 1279 | 1986-1995 | |
| 76 | Kevin Appier# | 1276 | 1989-1995 | |
| 77 | Dave Goltz | 1273 | 1976-1987 | |
| 78 | John Burkett# | 1272 | 1987-1995 | |
| 79 | Scott Bankhead# | 1268 | 1986-1995 | |
| 80 | Andy Benes# | 1264 | 1989-1995 | |
| 81 | Eric King# | 1245 | 1987-1995 | |
| 82 | Rick Reed# | 1238 | 1988-1995 | |
| 83 | Mark Guthrie# | 1231 | 1989-1995 | |
| 84 | Jim Clancy | 1225 | 1977-1991 | |
| 85 | Tim Belcher# | 1212 | 1987-1994 | |
| 86 | Curt Schilling# | 1181 | 1991-1995 | |
| 87 | Pat Zachry | 1175 | 1976-1989 | |
| 88 | Mark Fidrych | 1166 | 1976-1988 | |
| 89 | Bob Shirley | 1155 | 1977-1991 | |
| 90 | Joe Johnson# | 1140 | 1985-1995 | |
| 91 | Tom Seaver | 1137 | 1976-1986 | |
| 92 | Dennis Leonard | 1122 | 1976-1989 | |
| 93 | Mike Smithson | 1121 | 1982-1990 | |
| 94 | Ramon J. Martinez# | 1120 | 1988-1995 | |
| 95 | Pete Harnisch# | 1116 | 1989-1995 | |
| 96 | Dick Ruthven | 1110 | 1976-1987 | |
| 97 | Doug Drabek# | 1106 | 1987-1995 | |
| 98 | Frank Wills# | 1091 | 1984-1995 | |
| 99 | Pedro Martinez# | 1087 | 1992-1995 | |
| 99 | Gary Serum | 1087 | 1978-1988 |
