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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Dwight Gooden# | 3333 | 1984-1995 | |
| 2 | Dennis Eckersley | 2671 | 1976-1993 | |
| 3 | Floyd Youmans# | 2667 | 1985-1995 | |
| 4 | Bruce Hurst | 2656 | 1982-1994 | |
| 5 | Ed Correa# | 2649 | 1985-1995 | |
| 6 | Roger Clemens# | 2495 | 1984-1995 | |
| 7 | Jose Rijo# | 2489 | 1984-1995 | |
| 8 | Jose DeLeon# | 2472 | 1983-1995 | |
| 9 | Bill Gullickson# | 2425 | 1979-1995 | |
| 10 | Kevin Brown# | 2357 | 1986-1995 | |
| 11 | Jon Matlack* | 2330 | 1976-1990 | |
| 12 | Randy Johnson# | 2326 | 1989-1995 | |
| 13 | Scott Sanderson | 2319 | 1978-1992 | |
| 14 | Mike Scott | 2253 | 1979-1992 | |
| 15 | Greg Maddux# | 2244 | 1986-1995 | |
| 16 | Teddy Higuera# | 2161 | 1985-1995 | |
| 17 | Scott Garrelts# | 2160 | 1982-1995 | |
| 18 | Matt Young# | 2091 | 1983-1995 | |
| 19 | Marty Bystrom# | 2089 | 1980-1995 | |
| 20 | Bret Saberhagen# | 2081 | 1984-1995 | |
| 21 | Bob Sebra# | 2078 | 1985-1995 | |
| 22 | Frank Viola# | 2034 | 1982-1994 | |
| 23 | Orel Hershiser# | 2013 | 1983-1995 | |
| 24 | Ron Robinson# | 1967 | 1984-1995 | |
| 25 | Fernando Valenzuela | 1960 | 1980-1993 | |
| 26 | Jack Morris | 1951 | 1977-1990 | |
| 27 | Dan Warthen | 1931 | 1976-1992 | |
| 28 | John Fulgham | 1875 | 1979-1994 | |
| 29 | John Candelaria | 1872 | 1976-1990 | |
| 30 | Bob Ojeda# | 1866 | 1982-1995 | |
| 31 | Jimmy Key# | 1858 | 1984-1995 | |
| 32 | John Montefusco* | 1837 | 1976-1985 | |
| 33 | Silvio Martinez | 1816 | 1977-1993 | |
| 34 | Pascual Perez | 1801 | 1980-1993 | |
| 35 | Vida Blue* | 1795 | 1976-1990 | |
| 36 | Frank Tanana | 1760 | 1976-1988 | |
| 37 | Erik Hanson# | 1728 | 1988-1995 | |
| 38 | Bruce Ruffin# | 1715 | 1986-1995 | |
| 39 | Danny Jackson# | 1699 | 1983-1995 | |
| 40 | J.R. Richard | 1648 | 1976-1988 | |
| 41 | John Tudor | 1617 | 1979-1992 | |
| 42 | Roger Erickson | 1605 | 1978-1992 | |
| 42 | Mike Morgan# | 1605 | 1979-1995 | |
| 44 | Charlie Leibrandt | 1597 | 1979-1990 | |
| 45 | Bill C. Swift# | 1561 | 1985-1995 | |
| 46 | John Smiley# | 1558 | 1986-1995 | |
| 47 | Dennis Martinez | 1542 | 1976-1991 | |
| 48 | Mark Langston# | 1539 | 1984-1995 | |
| 49 | Atlee Hammaker | 1532 | 1981-1991 | |
| 50 | Kevin Gross# | 1525 | 1983-1994 | |
| 51 | Al Leiter# | 1505 | 1988-1995 | |
| 52 | Kelly Downs# | 1481 | 1986-1995 | |
| 53 | Joe Hesketh | 1447 | 1984-1993 | |
| 53 | Nolan Ryan | 1447 | 1976-1987 | |
| 55 | Rick Rhoden | 1446 | 1976-1992 | |
| 56 | Larry McWilliams | 1430 | 1978-1989 | |
| 57 | Melido Perez# | 1420 | 1987-1995 | |
| 58 | John Smoltz# | 1417 | 1988-1995 | |
| 59 | Jamie Moyer# | 1413 | 1987-1995 | |
| 60 | Bruce Berenyi | 1412 | 1980-1993 | |
| 61 | Zane Smith# | 1411 | 1984-1995 | |
| 62 | Steve Carlton | 1410 | 1976-1985 | |
| 63 | Jeff D. Robinson# | 1404 | 1984-1995 | |
| 64 | Andy Benes# | 1393 | 1989-1995 | |
| 65 | Pete Falcone | 1388 | 1976-1986 | |
| 65 | Steve Rogers | 1388 | 1976-1988 | |
| 67 | Kevin Appier# | 1385 | 1989-1995 | |
| 68 | Mike LaCoss | 1383 | 1978-1991 | |
| 69 | Scott Bankhead# | 1381 | 1986-1995 | |
| 70 | Rick Aguilera# | 1368 | 1985-1994 | |
| 71 | John Burkett# | 1362 | 1987-1995 | |
| 72 | Curt Schilling# | 1351 | 1991-1995 | |
| 73 | Tony Brizzolara | 1347 | 1980-1991 | |
| 74 | John Butcher | 1346 | 1980-1994 | |
| 75 | Mark Guthrie# | 1341 | 1989-1995 | |
| 76 | Rick Reed# | 1340 | 1988-1995 | |
| 77 | Eric King# | 1327 | 1987-1995 | |
| 78 | Mike Parrott | 1326 | 1977-1993 | |
| 79 | David Clyde | 1323 | 1976-1990 | |
| 80 | Andy Rincon | 1320 | 1980-1994 | |
| 81 | Pedro Martinez# | 1291 | 1992-1995 | |
| 82 | Frank Pastore | 1287 | 1979-1993 | |
| 83 | Kirk McCaskill# | 1286 | 1985-1995 | |
| 83 | Juan Nieves# | 1286 | 1986-1995 | |
| 85 | Dave Goltz | 1273 | 1976-1987 | |
| 86 | Ramon J. Martinez# | 1230 | 1988-1995 | |
| 87 | Jim Clancy | 1225 | 1977-1991 | |
| 88 | Tim Belcher# | 1212 | 1987-1994 | |
| 89 | Pete Harnisch# | 1211 | 1989-1995 | |
| 90 | Joe Johnson# | 1192 | 1985-1995 | |
| 91 | Mike Harkey# | 1177 | 1988-1995 | |
| 92 | Pat Zachry | 1175 | 1976-1989 | |
| 93 | Doug Drabek# | 1167 | 1987-1995 | |
| 94 | Mark Fidrych | 1166 | 1976-1988 | |
| 95 | Bob Shirley | 1155 | 1977-1991 | |
| 96 | Frank Wills# | 1154 | 1984-1995 | |
| 97 | Mike Mussina# | 1151 | 1991-1995 | |
| 98 | Tom Seaver | 1137 | 1976-1986 | |
| 99 | Dennis Leonard | 1122 | 1976-1989 | |
| 100 | Mike Smithson | 1121 | 1982-1990 |
