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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Jose DeLeon# | 163 | 1983-1995 | |
| 2 | Mike Scott | 140 | 1979-1992 | |
| 3 | Scott Garrelts# | 128 | 1982-1995 | |
| 4 | Dwight Gooden# | 127 | 1984-1995 | |
| 4 | Atlee Hammaker | 127 | 1981-1991 | |
| 4 | Bruce Hurst | 127 | 1982-1994 | |
| 7 | Randy Johnson# | 124 | 1989-1995 | |
| 8 | Greg Maddux# | 123 | 1986-1995 | |
| 9 | Teddy Higuera# | 122 | 1985-1995 | |
| 10 | Frank Viola# | 118 | 1982-1994 | |
| 11 | Kevin Brown# | 111 | 1986-1995 | |
| 12 | Silvio Martinez | 107 | 1977-1993 | |
| 13 | Matt Young# | 106 | 1983-1995 | |
| 14 | Bill Gullickson# | 103 | 1979-1995 | |
| 15 | Danny Jackson# | 101 | 1983-1995 | |
| 16 | John Smoltz# | 100 | 1988-1995 | |
| 17 | J.R. Richard | 96 | 1976-1988 | |
| 17 | Jose Rijo# | 96 | 1984-1995 | |
| 19 | Vida Blue* | 93 | 1976-1990 | |
| 20 | Mark Guthrie# | 89 | 1989-1995 | |
| 21 | Mike LaCoss | 87 | 1978-1991 | |
| 22 | Joe Johnson# | 83 | 1985-1995 | |
| 23 | Jon Matlack* | 79 | 1976-1990 | |
| 24 | Todd Van Poppel# | 75 | 1991-1995 | |
| 25 | Floyd Youmans# | 74 | 1985-1995 | |
| 26 | Steve Rogers | 73 | 1976-1988 | |
| 27 | Tony Brizzolara | 71 | 1980-1991 | |
| 28 | Frank Tanana | 70 | 1976-1988 | |
| 29 | Joe Hesketh | 69 | 1984-1993 | |
| 29 | Scott Sanderson | 69 | 1978-1992 | |
| 29 | Tom Seaver | 69 | 1976-1986 | |
| 32 | Rick Reed# | 67 | 1988-1995 | |
| 33 | Kevin Appier# | 66 | 1989-1995 | |
| 34 | Andy Rincon | 65 | 1980-1994 | |
| 35 | Bob Sebra# | 64 | 1985-1995 | |
| 36 | Ed Correa# | 63 | 1985-1995 | |
| 37 | Len Barker | 61 | 1976-1991 | |
| 37 | Roger Clemens# | 61 | 1984-1995 | |
| 39 | Dennis Eckersley | 59 | 1976-1993 | |
| 39 | Doc Medich | 59 | 1976-1984 | |
| 41 | Doug Drabek# | 57 | 1987-1995 | |
| 42 | Jerry Reuss | 56 | 1976-1986 | |
| 43 | Jeff D. Robinson# | 55 | 1984-1995 | |
| 44 | Jimmy Key# | 54 | 1984-1995 | |
| 44 | Randy Myers# | 54 | 1985-1995 | |
| 46 | Erik Hanson# | 52 | 1988-1995 | |
| 46 | Bill C. Swift# | 52 | 1985-1995 | |
| 48 | Roger Erickson | 51 | 1978-1992 | |
| 48 | Dennis Lamp | 51 | 1977-1988 | |
| 48 | Rick Rhoden | 51 | 1976-1992 | |
| 51 | Steve Avery# | 50 | 1990-1995 | |
| 51 | Dan Warthen | 50 | 1976-1992 | |
| 53 | Bill Caudill# | 48 | 1979-1994 | |
| 54 | Dennis Martinez | 46 | 1976-1991 | |
| 55 | Bryn Smith# | 45 | 1981-1995 | |
| 55 | John Tudor | 45 | 1979-1992 | |
| 57 | Tom Candiotti | 44 | 1984-1992 | |
| 57 | Charlie Leibrandt | 44 | 1979-1990 | |
| 59 | Wally Whitehurst# | 43 | 1989-1995 | |
| 60 | Steve Carlton | 42 | 1976-1985 | |
| 60 | Kevin Gross# | 42 | 1983-1994 | |
| 60 | Zane Smith# | 42 | 1984-1995 | |
| 63 | Alex Fernandez# | 41 | 1990-1995 | |
| 63 | Bob Knepper | 41 | 1976-1987 | |
| 63 | Pascual Perez | 41 | 1980-1993 | |
| 66 | Andy Benes# | 40 | 1989-1995 | |
| 66 | Kelly Downs# | 40 | 1986-1995 | |
| 66 | Joe Magrane# | 40 | 1987-1995 | |
| 69 | Ken Dayley | 38 | 1984-1992 | |
| 69 | Sid Fernandez | 38 | 1983-1988 | |
| 71 | Lynn McGlothen | 37 | 1976-1984 | |
| 71 | Gary Nolan | 37 | 1976-1984 | |
| 71 | Lee Smith# | 37 | 1980-1995 | |
| 71 | Kevin Tapani# | 37 | 1989-1994 | |
| 75 | Tim Belcher# | 36 | 1987-1994 | |
| 75 | John Candelaria | 36 | 1976-1990 | |
| 75 | Ken Howell# | 36 | 1984-1995 | |
| 75 | David West# | 36 | 1989-1995 | |
| 79 | Wilson Alvarez# | 35 | 1990-1995 | |
| 79 | Dave Goltz | 35 | 1976-1987 | |
| 81 | Bob James | 34 | 1978-1993 | |
| 81 | Jerry Koosman | 34 | 1976-1980 | |
| 81 | John Montefusco* | 34 | 1976-1985 | |
| 81 | Dan Plesac# | 34 | 1986-1995 | |
| 81 | Mark Portugal# | 34 | 1985-1995 | |
| 86 | Mark Littell | 33 | 1976-1988 | |
| 87 | Denny Neagle# | 32 | 1991-1995 | |
| 87 | Bret Saberhagen# | 32 | 1984-1995 | |
| 89 | Bert Blyleven | 31 | 1976-1985 | |
| 89 | Reggie Cleveland | 31 | 1976-1982 | |
| 91 | Bruce Berenyi | 30 | 1980-1993 | |
| 91 | Mike Bruhert | 30 | 1978-1986 | |
| 91 | Pete Falcone | 30 | 1976-1986 | |
| 91 | Catfish Hunter | 30 | 1976-1984 | |
| 91 | Doug Jones# | 30 | 1982-1995 | |
| 91 | Dan Petry | 30 | 1979-1987 | |
| 91 | Steve Renko | 30 | 1976-1983 | |
| 91 | Dave Stewart | 30 | 1978-1982 | |
| 99 | Jim Clancy | 29 | 1977-1991 | |
| 99 | Randy Tomlin# | 29 | 1990-1995 |
