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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Pedro Martinez# | 14.0 | 1992-1997 | |
| 2 | Len Barker | 11.7 | 1976-1991 | |
| 2 | Randy Johnson# | 11.7 | 1989-1997 | |
| 4 | Ed Correa# | 11.2 | 1985-1997 | |
| 5 | Randy Myers# | 10.9 | 1985-1997 | |
| 6 | Scott Sanders# | 10.8 | 1993-1997 | |
| 7 | John Smoltz# | 10.6 | 1988-1997 | |
| 8 | Dwight Gooden# | 10.0 | 1984-1997 | |
| 8 | David West# | 10.0 | 1989-1997 | |
| 10 | Teddy Higuera# | 9.9 | 1985-1997 | |
| 11 | Kelly Downs# | 9.3 | 1986-1997 | |
| 12 | Floyd Youmans# | 9.2 | 1985-1997 | |
| 13 | Kevin Appier# | 9.0 | 1989-1997 | |
| 13 | Dan Plesac# | 9.0 | 1986-1997 | |
| 15 | Scott Bankhead# | 8.9 | 1986-1997 | |
| 16 | Bob James | 8.8 | 1978-1993 | |
| 17 | Wilson Alvarez# | 8.7 | 1990-1997 | |
| 17 | Sid Fernandez | 8.7 | 1983-1988 | |
| 19 | Bill Caudill# | 8.5 | 1979-1994 | |
| 19 | Mike Mussina# | 8.5 | 1991-1997 | |
| 21 | J.R. Richard | 8.4 | 1976-1988 | |
| 21 | Denny Neagle# | 8.4 | 1991-1997 | |
| 23 | Todd Van Poppel# | 8.3 | 1991-1997 | |
| 24 | Scott Garrelts# | 8.2 | 1982-1997 | |
| 24 | Erik Hanson# | 8.2 | 1988-1997 | |
| 26 | Doug Jones# | 8.1 | 1982-1996 | |
| 26 | Jose DeLeon# | 8.1 | 1983-1997 | |
| 28 | Kevin Brown# | 8.0 | 1986-1997 | |
| 28 | John Montefusco* | 8.0 | 1976-1985 | |
| 28 | Greg Maddux# | 8.0 | 1986-1997 | |
| 28 | Rick Reed# | 8.0 | 1988-1997 | |
| 28 | Ken Dayley | 8.0 | 1984-1992 | |
| 28 | Ken Howell# | 8.0 | 1984-1996 | |
| 34 | Gregg Olson# | 7.9 | 1988-1997 | |
| 35 | Bert Blyleven | 7.8 | 1976-1985 | |
| 36 | Bob Sebra# | 7.7 | 1985-1997 | |
| 37 | Bruce Hurst | 7.6 | 1982-1994 | |
| 38 | Roger Clemens# | 7.5 | 1984-1997 | |
| 38 | Andy Pettitte# | 7.5 | 1995-1997 | |
| 38 | Steve Avery# | 7.5 | 1990-1997 | |
| 38 | Kevin Tapani# | 7.5 | 1989-1997 | |
| 42 | Andy Benes# | 7.4 | 1989-1997 | |
| 43 | Scott Karl# | 7.3 | 1996-1997 | |
| 43 | Tom Seaver | 7.3 | 1976-1986 | |
| 43 | John Burkett# | 7.3 | 1987-1997 | |
| 46 | Steve Carlton | 7.2 | 1976-1985 | |
| 46 | Marvin Freeman# | 7.2 | 1986-1997 | |
| 48 | Rheal Cormier# | 7.1 | 1991-1997 | |
| 48 | Kevin Gross# | 7.1 | 1983-1997 | |
| 48 | Joe Hesketh | 7.1 | 1984-1993 | |
| 51 | Jose Rijo# | 7.0 | 1984-1997 | |
| 51 | Randy Tomlin# | 7.0 | 1990-1997 | |
| 53 | Joey Hamilton# | 6.9 | 1994-1997 | |
| 53 | Dennis Eckersley | 6.9 | 1976-1993 | |
| 55 | Mark Guthrie# | 6.8 | 1989-1997 | |
| 55 | Lee Smith# | 6.8 | 1980-1997 | |
| 55 | Bryn Smith# | 6.8 | 1981-1996 | |
| 55 | Frank Viola# | 6.8 | 1982-1994 | |
| 59 | John Habyan# | 6.7 | 1985-1997 | |
| 59 | Danny Jackson | 6.7 | 1983-1996 | |
| 61 | Alex Fernandez# | 6.6 | 1990-1997 | |
| 61 | Tom Candiotti | 6.6 | 1984-1992 | |
| 63 | Ben McDonald# | 6.5 | 1989-1997 | |
| 64 | Scott Sanderson | 6.4 | 1978-1992 | |
| 65 | Joe Magrane# | 6.3 | 1987-1997 | |
| 65 | Mike Scott | 6.3 | 1979-1992 | |
| 67 | Mark Portugal# | 6.2 | 1985-1997 | |
| 67 | Rick Rhoden | 6.2 | 1976-1992 | |
| 67 | Butch Henry# | 6.2 | 1992-1997 | |
| 67 | Dan Warthen | 6.2 | 1976-1992 | |
| 67 | Al Holland | 6.2 | 1977-1987 | |
| 72 | Pascual Perez | 6.1 | 1980-1993 | |
| 72 | Frank Wills# | 6.1 | 1984-1997 | |
| 72 | Joe Johnson# | 6.1 | 1985-1997 | |
| 72 | Matt Young# | 6.1 | 1983-1997 | |
| 72 | Bill C. Swift# | 6.1 | 1985-1996 | |
| 72 | Doug Drabek# | 6.1 | 1987-1997 | |
| 78 | Steve Rogers | 6.0 | 1976-1988 | |
| 78 | Frank Tanana | 6.0 | 1976-1988 | |
| 78 | Steve Howe# | 6.0 | 1980-1995 | |
| 78 | Eric King# | 6.0 | 1987-1997 | |
| 78 | Dave Stewart | 6.0 | 1978-1982 | |
| 83 | Jerry Koosman | 5.9 | 1976-1980 | |
| 83 | Greg Swindell | 5.9 | 1986-1991 | |
| 83 | Steve Renko | 5.9 | 1976-1983 | |
| 83 | John Tudor | 5.9 | 1979-1992 | |
| 83 | Jon Matlack* | 5.9 | 1976-1990 | |
| 88 | Gary Nolan | 5.8 | 1976-1984 | |
| 88 | Atlee Hammaker | 5.8 | 1981-1991 | |
| 88 | Greg Mathews# | 5.8 | 1986-1997 | |
| 88 | Jim Clancy | 5.8 | 1977-1991 | |
| 88 | Mike Harkey# | 5.8 | 1988-1997 | |
| 93 | Dave Goltz | 5.7 | 1976-1987 | |
| 93 | Wally Whitehurst# | 5.7 | 1989-1997 | |
| 95 | Dennis Martinez | 5.6 | 1976-1991 | |
| 95 | Charlie Leibrandt | 5.6 | 1979-1990 | |
| 97 | Tony Brizzolara | 5.4 | 1980-1991 | |
| 97 | Bill Gullickson | 5.4 | 1979-1996 | |
| 97 | Ron Robinson# | 5.4 | 1984-1997 | |
| 100 | Miguel Batista# | 5.3 | 1992-1997 |
